STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGAP008147RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family. (506 aa)    
Predicted Functional Partners:
Q7PYJ8_ANOGA
AGAP001976-PA.
 
 0.973
Q7PMT7_ANOGA
ATP-dependent RNA helicase DDX1.
   
 0.940
A0NGX4_ANOGA
Homeobox prox 1.
   
 0.894
Q7PYA5_ANOGA
Homeobox prox 1.
   
 0.894
Q7Q2U7_ANOGA
RNA 3'-terminal phosphate cyclase.
  
  
 0.894
Q7Q8X5_ANOGA
RNA 3'-terminal phosphate cyclase-like protein.
  
  
 0.836
Q7PST4_ANOGA
AGAP011248-PA.
    
 0.726
Q7QHH7_ANOGA
AGAP011190-PA.
   
  
 0.718
Q7PLZ0_ANOGA
Eukaryotic peptide chain release factor subunit.
  
    0.715
eIF-4C
Translation initiation factor 4C (1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
      
 0.661
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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