STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hookProtein hook; Involved in endocytic trafficking. Probably acts as a cytoskeletal linker protein that tethers endosome vesicles to the cytoskeleton; Belongs to the hook family. (690 aa)    
Predicted Functional Partners:
AKTIP_ANOGA
Protein crossbronx homolog; Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
    
 
 0.816
U518_ANOGA
UPF0518 protein AGAP011705; Belongs to the UPF0518 family.
    
 0.649
Q7PR73_ANOGA
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 
 0.638
Q7QEC0_ANOGA
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 
 0.638
Q7PPI5_ANOGA
DNA helicase; Belongs to the MCM family.
   
 
 0.614
Q5TNU2_ANOGA
Protein bicaudal D homolog 2.
    
 
 0.586
Q7PQQ6_ANOGA
AGAP003125-PA.
    
 0.562
Q7QE59_ANOGA
AGAP000810-PA.
    
 0.554
Q7Q0L5_ANOGA
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
      
 0.534
Q7Q293_ANOGA
DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family.
     
 0.524
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.