STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F5HKL1_ANOGAAGAP002807-PB. (1778 aa)    
Predicted Functional Partners:
Q7PCX0_ANOGA
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.950
Q7Q8X9_ANOGA
AGAP010493-PA.
    
 
 0.936
Q7QJA8_ANOGA
DNA methyltransferase 1-associated protein 1.
    
 
 0.802
Q7QEU8_ANOGA
Histone arginine demethylase.
    
 
 0.746
Q7Q8M5_ANOGA
AGAP008541-PA; Belongs to the protein kinase superfamily.
    
 
 0.744
F5HIW4_ANOGA
Transcription initiation factor TFIID subunit 1.
    
 
0.720
Q7QF50_ANOGA
Histone H2A; Belongs to the histone H2A family.
    
 
 0.705
Q7Q1S4_ANOGA
YEATS domain-containing protein 4.
    
 
 0.667
Q7Q707_ANOGA
Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.
    
 
 0.660
Q7PPY4_ANOGA
AGAP005152-PA.
    
 
 0.615
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.