STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F5HMB9_ANOGA1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)    
Predicted Functional Partners:
Q7PTM6_ANOGA
Inactivation no afterpotential D protein.
   
 0.997
Q7PW25_ANOGA
Phosphoinositide phospholipase C.
  
 
0.946
Q7QEY1_ANOGA
Inositol-1,4,5-trisphosphate 5-phosphatase.
   
 
 0.931
Q7QHE3_ANOGA
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
0.930
Q7Q042_ANOGA
AGAP012252-PA; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
   
 
 0.928
A7URB5_ANOGA
Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family.
     
 0.924
Q7PZU9_ANOGA
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.922
Q7Q237_ANOGA
Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family.
     
 0.919
Q7PYY6_ANOGA
Inositol-1,4,5-trisphosphate 5-phosphatase.
     
 0.916
Q7PNQ6_ANOGA
Inositol-1-monophosphatase.
     
 0.913
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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