STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CecACecropin-A amidated isoform; Antibacterial activity against several Gram-positive and Gram-negative bacteria. Antifungal activity against A.fumigatus, B.cinerea, F.culmorum, F.oxysporum, N.crassa, C.albicans, C.neoformans and S.cerevisiae. (58 aa)    
Predicted Functional Partners:
REL2
IMD pathway signalling NF-kappaB Relish-like transcription factor.
     
 0.971
gambif1
AGAP009515-PA.
     
 0.955
Def1
Defensin; Responsible for the anti Gram-positive activity of immune hemolymph; Belongs to the invertebrate defensin family. Type 1 subfamily.
   
  
 0.891
irsp
Putative infection responsive short peptide.
      
 0.721
IMD
IMD pathway signalling Immune Deficiency (Imd).
      
 0.691
LYSC1_ANOGA
Lysozyme c-1; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
      
 0.580
TEP1
AGAP010815-PA.
      
 0.580
TEP1-2
AGAP010815-PA.
      
 0.580
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.