STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Act5CActin-5C; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction; Belongs to the actin family. (376 aa)    
Predicted Functional Partners:
Q7PSN7_ANOGA
AGAP011099-PA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.923
Q7Q1L3_ANOGA
AGAP009730-PA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.923
Q7Q0S6_ANOGA
AGAP010186-PA.
     
  0.900
Q7Q0S7_ANOGA
AGAP010184-PA.
     
  0.900
Q7PJ49_ANOGA
AGAP008100-PA.
    
 0.788
Actn
Alpha-actinin, sarcomeric; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity); Belongs to the alpha-actinin family.
   
 0.785
Q7Q1U8_ANOGA
Glyceraldehyde-3-phosphate dehydrogenase.
   
 
 0.746
RpS7
40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.
   
 
 0.735
DCTN2-p50
Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis.
    
 0.715
Q7Q8D3_ANOGA
Actin-like protein 6B; Belongs to the actin family.
    
0.710
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.