STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5TWZ8_ANOGACoronin; Belongs to the WD repeat coronin family. (635 aa)    
Predicted Functional Partners:
Q7Q0L5_ANOGA
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
    
 0.867
Q7QHT9_ANOGA
Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
    
 0.837
Q5TSB4_ANOGA
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
    
 0.809
Q7QDW7_ANOGA
Thymidylate synthase.
    
 0.735
Q7Q5H2_ANOGA
GTP cyclohydrolase I.
    
 0.700
Q7Q627_ANOGA
Molybdenum cofactor biosynthesis protein.
    
 0.685
Q7Q0U6_ANOGA
AGAP010159-PA.
      0.668
Q7QC97_ANOGA
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.645
Q7PUV9_ANOGA
Ubiquitin conjugation factor E4 A.
     
 0.628
Q7Q3H0_ANOGA
AGAP007870-PA.
     
 0.628
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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