STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7PN71_ANOGAAGAP007825-PA. (670 aa)    
Predicted Functional Partners:
Q7QII3_ANOGA
Pre-mRNA-processing factor 8.
   
 0.997
Q7PZ10_ANOGA
AGAP011677-PA.
   
 0.995
Q7Q6W1_ANOGA
Pre-mRNA-processing factor 6.
   
 0.995
Q7Q496_ANOGA
Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.
    
 0.991
Q7QG51_ANOGA
U5 snRNP complex subunit.
    
 0.990
Q7PXQ1_ANOGA
Pre-mRNA-splicing helicase BRR2.
   
 0.989
Q7Q2A9_ANOGA
Small nuclear ribonucleoprotein Sm D2.
    
 0.984
Q7Q0C0_ANOGA
Small nuclear ribonucleoprotein Sm D3.
   
 0.979
Q7PT70_ANOGA
Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.
    
 0.978
AGAP001584
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
    
 0.974
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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