STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UFC1_ANOGAUbiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (167 aa)    
Predicted Functional Partners:
Q7PWD0_ANOGA
Ubiquitin-like modifier-activating enzyme 5.
  
 
 
 0.975
UFM1_ANOGA
Ubiquitin-fold modifier 1; Ubiquitin-like modifier protein which binds to a number of as yet unidentified target proteins.
   
 
 0.895
UFL1_ANOGA
E3 UFM1-protein ligase 1 homolog; E3 UFM1-protein ligase that mediates ufmylation of target proteins.
    
 
 0.749
Q7PZM0_ANOGA
AGAP011975-PA.
  
  
 0.745
F5HLA5_ANOGA
DDRGK domain-containing protein 1.
    
 
 0.734
Q7Q749_ANOGA
Ufm1-specific protease 1.
  
  
 0.656
MOCS3_ANOGA
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
    
 
 0.569
Q7Q1F7_ANOGA
AGAP009811-PA.
   
 
 0.540
Q7Q9Q6_ANOGA
Autophagy related gene.
    
 
 0.454
Q7Q7Q1_ANOGA
AGAP004626-PA.
   
  
 0.436
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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