GSTE2 protein (Anopheles gambiae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GSTE2

Glutathione S-transferase epsilon class 2. (221 aa)

Predicted Functional Partners:

GstS1

0.800

Q7PRA2_ANOGA

0.799

GSTo1

0.784

CYP6Z1

0.767

gstT2

0.741

GSTD3

0.730

GSTe8

0.730

Ace

0.727

cyp9k1

0.726

gstT1

0.722

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ace	CYP6Z1	Q869C3	Q7Q452	Acetylcholinesterase; Rapidly hydrolyzes choline released into the synapse. Belongs to the type-B carboxylesterase/lipase family.	Cytochrome P450; Belongs to the cytochrome P450 family.	0.683
Ace	GSTE2	Q869C3	Q7PVS6	Acetylcholinesterase; Rapidly hydrolyzes choline released into the synapse. Belongs to the type-B carboxylesterase/lipase family.	Glutathione S-transferase epsilon class 2.	0.727
Ace	cyp9k1	Q869C3	Q8T633	Acetylcholinesterase; Rapidly hydrolyzes choline released into the synapse. Belongs to the type-B carboxylesterase/lipase family.	Cytochrome P450 CYP9K1; Belongs to the cytochrome P450 family.	0.580
CYP6Z1	Ace	Q7Q452	Q869C3	Cytochrome P450; Belongs to the cytochrome P450 family.	Acetylcholinesterase; Rapidly hydrolyzes choline released into the synapse. Belongs to the type-B carboxylesterase/lipase family.	0.683
CYP6Z1	GSTE2	Q7Q452	Q7PVS6	Cytochrome P450; Belongs to the cytochrome P450 family.	Glutathione S-transferase epsilon class 2.	0.767
CYP6Z1	cyp9k1	Q7Q452	Q8T633	Cytochrome P450; Belongs to the cytochrome P450 family.	Cytochrome P450 CYP9K1; Belongs to the cytochrome P450 family.	0.501
GSTD3	GSTE2	Q7PQ95	Q7PVS6	Glutathione S-transferase delta class 3; Belongs to the GST superfamily.	Glutathione S-transferase epsilon class 2.	0.730
GSTD3	GSTe8	Q7PQ95	Q8WQJ5	Glutathione S-transferase delta class 3; Belongs to the GST superfamily.	Glutathione S-transferase e8; Belongs to the GST superfamily.	0.701
GSTD3	GSTo1	Q7PQ95	Q86D85	Glutathione S-transferase delta class 3; Belongs to the GST superfamily.	Glutathione S-transferase omega class 1; Belongs to the GST superfamily.	0.753
GSTD3	GstS1	Q7PQ95	P46428	Glutathione S-transferase delta class 3; Belongs to the GST superfamily.	Glutathione S-transferase; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Sigma family.	0.752
GSTD3	Q7PRA2_ANOGA	Q7PQ95	Q7PRA2	Glutathione S-transferase delta class 3; Belongs to the GST superfamily.	Bifunctional glutamyl/prolyl-tRNA synthetase.	0.799
GSTD3	cyp9k1	Q7PQ95	Q8T633	Glutathione S-transferase delta class 3; Belongs to the GST superfamily.	Cytochrome P450 CYP9K1; Belongs to the cytochrome P450 family.	0.573
GSTD3	gstT1	Q7PQ95	Q8MUQ1	Glutathione S-transferase delta class 3; Belongs to the GST superfamily.	Glutathione S-transferase theta class 1; Belongs to the GST superfamily.	0.728
GSTD3	gstT2	Q7PQ95	Q8MUQ2	Glutathione S-transferase delta class 3; Belongs to the GST superfamily.	Glutathione S-transferase theta class 2; Belongs to the GST superfamily.	0.831
GSTE2	Ace	Q7PVS6	Q869C3	Glutathione S-transferase epsilon class 2.	Acetylcholinesterase; Rapidly hydrolyzes choline released into the synapse. Belongs to the type-B carboxylesterase/lipase family.	0.727
GSTE2	CYP6Z1	Q7PVS6	Q7Q452	Glutathione S-transferase epsilon class 2.	Cytochrome P450; Belongs to the cytochrome P450 family.	0.767
GSTE2	GSTD3	Q7PVS6	Q7PQ95	Glutathione S-transferase epsilon class 2.	Glutathione S-transferase delta class 3; Belongs to the GST superfamily.	0.730
GSTE2	GSTe8	Q7PVS6	Q8WQJ5	Glutathione S-transferase epsilon class 2.	Glutathione S-transferase e8; Belongs to the GST superfamily.	0.730
GSTE2	GSTo1	Q7PVS6	Q86D85	Glutathione S-transferase epsilon class 2.	Glutathione S-transferase omega class 1; Belongs to the GST superfamily.	0.784
GSTE2	GstS1	Q7PVS6	P46428	Glutathione S-transferase epsilon class 2.	Glutathione S-transferase; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Sigma family.	0.800