STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7PXN6_ANOGAAGAP001492-PA. (570 aa)    
Predicted Functional Partners:
Q7Q372_ANOGA
Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
 
      0.780
Q7PCX0_ANOGA
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
   0.445
Q7PPE7_ANOGA
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.440
F5HKF0_ANOGA
Poly(U)-specific endoribonuclease.
      
 0.420
Q7Q4R9_ANOGA
Alanine transaminase.
     
 0.420
Q7Q1U8_ANOGA
Glyceraldehyde-3-phosphate dehydrogenase.
      
 0.418
Q7QCB7_ANOGA
Nicalin; Belongs to the nicastrin family.
   
  
 0.410
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.