STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7PY83_ANOGAAGAP001792-PA. (597 aa)    
Predicted Functional Partners:
Dox-A2
Probable 26S proteasome non-ATPase regulatory subunit 3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
   
  
 0.693
Q7QI51_ANOGA
Evolutionarily conserved signaling intermediate in Toll pathways.
   
   0.690
Q5TTS2_ANOGA
AGAP002481-PA.
      
 0.667
Q7PXS8_ANOGA
AGAP001549-PA.
      
 0.667
Q7PY49_ANOGA
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
      
 0.667
Q7Q4W4_ANOGA
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1.
    
   0.657
Q7Q515_ANOGA
Spectrin alpha.
    
 
 0.585
Q7QBC9_ANOGA
Histone acetyltransferase type B subunit 2.
      
 0.576
Q7PNA9_ANOGA
60S ribosomal protein LP1; Belongs to the eukaryotic ribosomal protein P1/P2 family.
      
 0.560
Q7QG40_ANOGA
AGAP009486-PA.
      
 0.538
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.