STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCD22_ANOGACoiled-coil domain-containing protein 22 homolog; Belongs to the CCDC22 family. (557 aa)    
Predicted Functional Partners:
Q7QC18_ANOGA
COMM domain-containing protein 2.
    
 0.975
Q7PW94_ANOGA
AGAP009044-PA.
    
 
 0.959
Q7PX47_ANOGA
COMM domain-containing protein 4.
    
 0.925
Q380B5_ANOGA
AGAP001150-PA.
    
 
 0.856
Q7QK27_ANOGA
Down syndrome critical region protein 3-like protein.
   
 
 0.794
Q7PQH5_ANOGA
AGAP003605-PA; Belongs to the cullin family.
    
 0.699
Q7Q3Y9_ANOGA
AGAP008105-PA; Belongs to the cullin family.
    
 0.677
Q7QBW4_ANOGA
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.674
Q7Q7Y5_ANOGA
G protein pathway suppressor 1.
   
 
  0.673
Q7PNC6_ANOGA
AGAP008007-PA; Belongs to the cullin family.
    
 0.672
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.