STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7Q1L2_ANOGAProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (333 aa)    
Predicted Functional Partners:
Q7PV65_ANOGA
AGAP011770-PA.
    
 0.961
por
Protein-serine O-palmitoleoyltransferase porcupine; Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1), to Wnt proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors.
    
 0.943
Q7Q626_ANOGA
AGAP006073-PA.
    
 0.920
Q7QER8_ANOGA
AGAP000117-PA.
    
 0.916
GPRFZ1A
AGAP011380-PA; Belongs to the G-protein coupled receptor Fz/Smo family.
  
 
 0.878
GPRFZ3
AGAP000168-PA; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.871
Q5TPW4_ANOGA
AGAP011379-PA.
  
 
 0.854
GPRFZ1B
AGAP011382-PA; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.840
GPRFZ2
Frizzled 2 transmembrane receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.827
GPRFZ4
AGAP008871-PA; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.816
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.