STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7QAS7_ANOGAAGAP003559-PA; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (741 aa)    
Predicted Functional Partners:
GPRFZ2
Frizzled 2 transmembrane receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.921
GPRFZ3
AGAP000168-PA; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.912
GPRFZ1A
AGAP011380-PA; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.911
GPRFZ1B
AGAP011382-PA; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.911
Q5TPW4_ANOGA
AGAP011379-PA.
     
 0.910
GPRFZ4
AGAP008871-PA; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.910
Q7Q626_ANOGA
AGAP006073-PA.
    
 0.827
Q7QJU1_ANOGA
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.796
Q7PXI1_ANOGA
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.768
Q7Q428_ANOGA
Heparan sulfate 2-O-sulfotransferase HS2ST1.
     
 0.756
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.