STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7QAW5_ANOGAHistone-lysine N-methyltransferase SETD8. (579 aa)    
Predicted Functional Partners:
A0NGA2_ANOGA
AGAP009131-PA.
     
 0.908
Q7PXP4_ANOGA
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase.
    
  0.902
Q7PCX0_ANOGA
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.808
Q7Q0Q0_ANOGA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
   0.617
Q7Q8T2_ANOGA
AGAP010575-PA.
    
 0.522
Q7QF50_ANOGA
Histone H2A; Belongs to the histone H2A family.
   
 0.449
Q7QBC9_ANOGA
Histone acetyltransferase type B subunit 2.
   
 0.433
Q5TQ82_ANOGA
AGAP008505-PA.
    
 0.432
Q7PUT3_ANOGA
AGAP001895-PA.
    
 0.417
Q5TT37_ANOGA
Set1/Ash2 histone methyltransferase complex subunit ASH2.
    
 0.409
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.