STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7QFA1_ANOGAAGAP000378-PA. (422 aa)    
Predicted Functional Partners:
H2KMF4_ANOGA
AGAP009863-PA; Belongs to the DEAD box helicase family.
   
 0.934
Q7PRK8_ANOGA
Reversion-inducing cysteine-rich protein with Kazal motifs.
      
 0.589
A7UVL2_ANOGA
AGAP002131-PA.
      
 0.550
Q5TPC4_ANOGA
AGAP009628-PA.
      
 0.509
Q7PP27_ANOGA
AGAP006246-PA.
     
 0.506
Q5TQK8_ANOGA
AGAP008087-PA.
      
 0.461
Q7PYH7_ANOGA
AGAP001944-PA.
    
 
 0.442
A0NCC6_ANOGA
Translation initiation factor 4B.
      
 0.439
AGAP005129
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
      
 0.408
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.