STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7QHI1_ANOGAAGAP011193-PA. (194 aa)    
Predicted Functional Partners:
Q7PCX0_ANOGA
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.836
Q7PNC3_ANOGA
Replication factor A2.
    
 0.798
Q7Q186_ANOGA
AGAP009921-PA.
    
   0.618
Q7QF50_ANOGA
Histone H2A; Belongs to the histone H2A family.
 
 
 0.570
Q7Q2C5_ANOGA
Histone H2B; Belongs to the histone H2B family.
 
 
 0.462
Q5TSV8_ANOGA
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.461
Q7Q6I9_ANOGA
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
    
 0.461
Q7Q6Q3_ANOGA
AGAP005729-PA; Belongs to the protein kinase superfamily.
    
 0.461
Q7QKF5_ANOGA
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.461
Q7PD39_ANOGA
Histone H3; Belongs to the histone H3 family.
 
 
 0.450
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.