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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECL_00538FxsA. (154 aa)    
Predicted Functional Partners:
ECL_01839
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
    
  0.911
ECL_03760
Malic enzyme.
    
  0.848
ECL_01259
Putative thioredoxin-like protein.
   
    0.834
hslV
ATP-dependent HslUV protease, peptidase subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
    0.834
ECL_00712
Amidohydrolase 3.
  
    0.824
accA
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
    
  0.706
ECL_04640
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
    
  0.706
ECL_04641
acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
    
  0.706
ECL_02194
Putative allophanate hydrolase.
    
  0.662
hslU
ATP-dependent HslUV protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
   
    0.654
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.