Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECL_02269DNA-binding transcriptional regulator RstA. (238 aa)    
Predicted Functional Partners:
ECL_02271
Sensor protein RstB.
 
 0.979
ECL_04591
Aerobic respiration control sensor protein ArcB.
 
 0.978
ECL_04118
Hybrid sensory histidine kinase BarA.
 
 0.969
ECL_00717
PAS sensor protein.
   
 0.911
ECL_04447
Two-component system, NarL family, sensor histidine kinase EvgS.
 
 0.850
ECL_05065
Two-component system, OmpR family, sensor histidine kinase CpxA.
 
 0.847
ECL_02505
Sensor protein PhoQ.
 
 0.824
ECL_00346
Integral membrane sensor hybrid histidine kinase.
   
 0.814
ECL_04563
Sensor protein BasS/PmrB.
 
 0.788
nuoC
NADH:ubiquinone oxidoreductase, chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
   0.780
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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