Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECL_02460Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)    
Predicted Functional Partners:
ECL_04602
Glutamate synthase large subunit.
  
 0.996
ECL_01839
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.979
ECL_02619
Trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
 
 0.979
ECL_02725
Aromatic amino acid aminotransferase.
   
 0.962
ECL_02194
Putative allophanate hydrolase.
  
 
 0.953
ECL_03012
Citrate synthase; Belongs to the citrate synthase family.
   
 0.952
ECL_04603
Glutamate synthase (NADPH/NADH) small subunit.
  
 
 0.938
argA
N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily.
  
 
 0.936
ECL_02498
Isocitrate dehydrogenase.
   
 0.934
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.934
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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