Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
ECL_03031Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (176 aa)    
Predicted Functional Partners:
fur
Ferric uptake regulator; Belongs to the Fur family.
  
  
 0.771
ECL_03106
Isochorismatase.
   
    0.766
ECL_03030
LexA regulated protein.
 
  
 0.738
ECL_01839
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
 
   
 0.679
seqA
Replication initiation regulator SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
 
  
 0.562
ECL_03027
Phosphoglucomutase.
     
 0.537
ECL_00487
Putative NADH oxidase.
    
  0.521
entE
Enterobactin 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase.
   
    0.428
ECL_03029
Hypothetical protein.
       0.405
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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