Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gmdGDPmannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (373 aa)    
Predicted Functional Partners:
fcl
GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
 0.999
manB
Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 
 0.997
wcaI
Colanic acid biosynthesis glycosyl transferase WcaI.
 
 
 0.990
wcaH
Colanic acid biosynthesis protein WcaH; Hydrolyzes GDP-mannose; Belongs to the Nudix hydrolase family.
 
  
 0.990
wcaF
Putative colanic acid biosynthesis acetyltransferase WcaF.
 
 
 0.976
ECL_03353
Sugar transferases involved in lipopolysaccharide synthesis.
  
  
 0.963
wcaE
Putative colanic acid biosynthesis glycosyl transferase WcaE.
 
 
 0.963
ECL_03380
Putative glycosyl transferase.
  
 
 0.962
wcaJ
Putative colanic acid biosysnthesis UDP-glucose lipid carrier.
  
  
 0.879
ECL_03364
Psb1.
  
  
 0.876
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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