Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECL_03428Phosphotyrosine-protein phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (149 aa)    
Predicted Functional Partners:
ECL_03427
Cryptic autophosphorylating protein tyrosine kinase Etk.
 
 0.971
ECL_03429
Polysaccharide export protein.
 
 
 0.946
ECL_03383
Tyrosine kinase.
 
 0.889
ECL_01022
Tyrosine kinase.
 
 0.887
ECL_01020
Putative polysaccharide export protein.
 
 
 0.759
ECL_03385
Polysaccharide export protein.
 
 0.759
ECL_01932
Hypothetical protein; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
   
   0.663
ECL_03353
Sugar transferases involved in lipopolysaccharide synthesis.
  
 
 0.625
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.625
ECL_00573
FtsH protease regulator HflC; HflC and HflK could regulate a protease.
  
    0.613
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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