close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECL_03450Multidrug resistance outer membrane protein MdtQ. (472 aa)    
Predicted Functional Partners:
ECL_00381
Macrolide-specific ABC-type efflux carrier; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
  
 
 0.895
macB
Macrolide transporter ATP-binding /permease protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.895
ECL_04022
Efflux pump membrane protein.
 
 0.812
ECL_04649
RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  0.778
eefA
Multidrug efflux periplasmic linker protein EefA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  0.774
acrA
AcrA protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.770
oqxA
RND family multidrug efflux membrane fusion protein OqxA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  0.751
ECL_02911
Putative multidrug resistance protein K.
 
 0.737
ECL_02087
Putative multidrug efflux protein.
 
 0.734
ECL_03150
RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  0.727
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.