| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECL_00717 | folE | ECL_00717 | ECL_03462 | PAS sensor protein. | GTP cyclohydrolase I. | 0.941 |
| ECL_00717 | moaA | ECL_00717 | ECL_02953 | PAS sensor protein. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.948 |
| ECL_00717 | ribA | ECL_00717 | ECL_01744 | PAS sensor protein. | Hypothetical protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 0.949 |
| ECL_00946 | ECL_03652 | ECL_00946 | ECL_03652 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase. | 0.930 |
| ECL_00946 | ECL_03814 | ECL_00946 | ECL_03814 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.989 |
| ECL_00946 | ECL_04107 | ECL_00946 | ECL_04107 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | Putative 6-pyruvoyl tetrahydrobiopterin synthase. | 0.417 |
| ECL_00946 | ECL_04384 | ECL_00946 | ECL_04384 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | Bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.996 |
| ECL_00946 | ECL_04556 | ECL_00946 | ECL_04556 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| ECL_00946 | folE | ECL_00946 | ECL_03462 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | GTP cyclohydrolase I. | 0.995 |
| ECL_00946 | moaA | ECL_00946 | ECL_02953 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.495 |
| ECL_00946 | ribA | ECL_00946 | ECL_01744 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | Hypothetical protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 0.758 |
| ECL_01433 | ECL_03652 | ECL_01433 | ECL_03652 | dATP pyrophosphohydrolase. | D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase. | 0.894 |
| ECL_01433 | ECL_04107 | ECL_01433 | ECL_04107 | dATP pyrophosphohydrolase. | Putative 6-pyruvoyl tetrahydrobiopterin synthase. | 0.895 |
| ECL_01433 | folE | ECL_01433 | ECL_03462 | dATP pyrophosphohydrolase. | GTP cyclohydrolase I. | 0.908 |
| ECL_03652 | ECL_00946 | ECL_03652 | ECL_00946 | D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase. | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase. | 0.930 |
| ECL_03652 | ECL_01433 | ECL_03652 | ECL_01433 | D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase. | dATP pyrophosphohydrolase. | 0.894 |
| ECL_03652 | ECL_03814 | ECL_03652 | ECL_03814 | D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.878 |
| ECL_03652 | ECL_04107 | ECL_03652 | ECL_04107 | D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase. | Putative 6-pyruvoyl tetrahydrobiopterin synthase. | 0.922 |
| ECL_03652 | ECL_04556 | ECL_03652 | ECL_04556 | D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.879 |
| ECL_03652 | folE | ECL_03652 | ECL_03462 | D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase. | GTP cyclohydrolase I. | 0.990 |