Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECL_03465Colicin I receptor. (640 aa)    
Predicted Functional Partners:
ECL_01647
Transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 0.952
ECL_03106
Isochorismatase.
  
  
 0.903
ECL_03117
Iron complex outermembrane recepter protein.
  
   
0.885
entC
Isochorismate synthase.
   
  
 0.883
ECL_03116
Enterobactin/ferric enterobactin esterase.
  
  
 0.869
ECL_02534
Ferric-rhodotorulic acid outer membrane transporter.
  
  
 0.854
entE
Enterobactin 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase.
 
  
 0.832
ECL_01520
TonB-dependent siderophore receptor.
   
  
 0.831
ECL_03105
2,3-dihydroxybenzoate-2,3-dehydrogenase.
   
  
 0.805
entH
Hypothetical protein; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family.
  
    0.778
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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