nfo protein (Enterobacter cloacae) - STRING interaction network

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nfo

Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (285 aa)

Predicted Functional Partners:

ECL_02450

0.942

nth

0.873

ung

0.646

ECL_03468

0.634

ECL_00856

0.627

ECL_03391

0.581

ECL_05067

0.570

ECL_02337

0.567

ECL_00491

0.496

recA

0.487

Your Current Organism:

Enterobacter cloacae

NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ECL_00491	nfo	ECL_00491	ECL_03469	Inorganic diphosphatase.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.496
ECL_00856	ECL_02450	ECL_00856	ECL_02450	DNA polymerase II.	Exonuclease III.	0.882
ECL_00856	ECL_03391	ECL_00856	ECL_03391	DNA polymerase II.	3-methyl-adenine DNA glycosylase II.	0.599
ECL_00856	nfo	ECL_00856	ECL_03469	DNA polymerase II.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.627
ECL_00856	nth	ECL_00856	ECL_02312	DNA polymerase II.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.500
ECL_00856	recA	ECL_00856	ECL_04033	DNA polymerase II.	Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.897
ECL_02337	nfo	ECL_02337	ECL_03469	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.567
ECL_02337	recA	ECL_02337	ECL_04033	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.513
ECL_02450	ECL_00856	ECL_02450	ECL_00856	Exonuclease III.	DNA polymerase II.	0.882
ECL_02450	ECL_03391	ECL_02450	ECL_03391	Exonuclease III.	3-methyl-adenine DNA glycosylase II.	0.923
ECL_02450	nfo	ECL_02450	ECL_03469	Exonuclease III.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.942
ECL_02450	nth	ECL_02450	ECL_02312	Exonuclease III.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.985
ECL_02450	recA	ECL_02450	ECL_04033	Exonuclease III.	Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.471
ECL_02450	ung	ECL_02450	ECL_03916	Exonuclease III.	uracil-DNA-glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.900
ECL_03391	ECL_00856	ECL_03391	ECL_00856	3-methyl-adenine DNA glycosylase II.	DNA polymerase II.	0.599
ECL_03391	ECL_02450	ECL_03391	ECL_02450	3-methyl-adenine DNA glycosylase II.	Exonuclease III.	0.923
ECL_03391	nfo	ECL_03391	ECL_03469	3-methyl-adenine DNA glycosylase II.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.581
ECL_03391	nth	ECL_03391	ECL_02312	3-methyl-adenine DNA glycosylase II.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.533
ECL_03391	recA	ECL_03391	ECL_04033	3-methyl-adenine DNA glycosylase II.	Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.524
ECL_03468	nfo	ECL_03468	ECL_03469	Hypothetical protein; Belongs to the UPF0324 family.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.634

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