Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECL_03473Bifunctional fructose-specific PTS IIA/HPr protein. (376 aa)    
Predicted Functional Partners:
ECL_03001
PTS system, fructose-specific II ABC component.
 
 
0.999
ECL_03470
Hypothetical protein.
 
 
 0.999
ECL_03746
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 0.999
ECL_00170
PTS system, mannitol-specific IIC subunit.
 
0.997
ECL_03471
1-phosphofructokinase.
 
 
 0.997
ECL_03472
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.997
ECL_01487
PTS system, mannose-specific IIAB component.
 
 
 0.993
ECL_03036
N-acetyl glucosamine specific PTS system components IIABC.
 
 0.988
ECL_04151
Putative phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.
 
 
 0.982
ECL_02424
6-phosphofructokinase 2; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.970
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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