Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECL_03491Fructuronate reductase; Belongs to the mannitol dehydrogenase family. (488 aa)    
Predicted Functional Partners:
ECL_00170
PTS system, mannitol-specific IIC subunit.
 
 
 0.981
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
 
 0.963
ECL_03001
PTS system, fructose-specific II ABC component.
  
 
 0.909
ECL_03473
Bifunctional fructose-specific PTS IIA/HPr protein.
  
 
 0.906
ECL_03470
Hypothetical protein.
  
 
 0.865
uxaC-2
Glucuronate isomerase.
 
 
 0.853
uxaC
Glucuronate isomerase.
 
 
 0.852
ECL_04491
D-altronate dehydratase.
 
 
 0.731
manB
Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.712
ECL_01929
Aminoimidazole riboside kinase; Belongs to the carbohydrate kinase PfkB family.
    
 0.646
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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