Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECL_04058NADH ubiquinone oxidoreductase, 20 kDa subunit. (255 aa)    
Predicted Functional Partners:
ECL_04060
NADH dehydrogenase (ubiquinone), 30 kDa subunit.
 
 0.999
ECL_04061
Formate hydrogenlyase subunit 4.
 
 
 0.998
ECL_04059
Formate hydrogenlyase complex iron-sulfur subunit.
 
 
 0.997
ECL_04062
Formate hydrogenlyase subunit 3.
 
 
 0.996
ECL_04063
Formate hydrogenlyase subunit 2.
 
 
 0.989
nuoC
NADH:ubiquinone oxidoreductase, chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
 
 0.975
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
 
 0.967
ECL_04056
Hydrogenase 3 maturation protease.
 
  
 0.964
ECL_04057
Hydrogenase 3 large subunit processing protein.
 
  
 0.964
ECL_01839
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.948
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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