Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECL_04064Formate hydrogenlyase regulatory protein HycA. (154 aa)    
Predicted Functional Partners:
ECL_04063
Formate hydrogenlyase subunit 2.
  
  
 0.956
ECL_04060
NADH dehydrogenase (ubiquinone), 30 kDa subunit.
  
  
 0.954
ECL_04059
Formate hydrogenlyase complex iron-sulfur subunit.
  
    0.825
ECL_04061
Formate hydrogenlyase subunit 4.
  
    0.820
ECL_04058
NADH ubiquinone oxidoreductase, 20 kDa subunit.
  
  
 0.800
ECL_04057
Hydrogenase 3 large subunit processing protein.
  
  
 0.787
ECL_04062
Formate hydrogenlyase subunit 3.
  
  
 0.770
ECL_04056
Hydrogenase 3 maturation protease.
  
  
 0.695
ECL_04071
NifA subfamily transcriptional regulator.
     
 0.597
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
  
 0.588
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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