Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hypAHydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (116 aa)    
Predicted Functional Partners:
ECL_04067
Hydrogenase nickel incorporation protein HypB.
 
 
 0.998
ECL_04068
Hydrogenase expression/formation protein HypC.
 
  
 0.986
ECL_04069
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.973
ECL_04070
Hydrogenase expression/formation protein HypE.
 
  
 0.970
ECL_04060
NADH dehydrogenase (ubiquinone), 30 kDa subunit.
 
 
 0.923
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
 
 0.901
ECL_04050
Hydrogenase maturation protein HypF.
 
   
 0.860
ECL_04051
Hydrogenase maturation protein HypF.
 
   
 0.860
ECL_00193
Putative hydrogenase, 4Fe-4S ferredoxin-type component.
  
  
 0.696
ECL_04063
Formate hydrogenlyase subunit 2.
  
  
 0.682
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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