Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (448 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase.
 
 
 0.998
ECL_00669
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 
 0.994
carB
Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
 
 
 0.992
argE
Acetylornithine deacetylase.
  
 0.992
ECL_00678
Phage ornithine carbamoyltransferase 2, chain F; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 
 0.989
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.
 
  
 0.981
argA
N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily.
 
 
 0.970
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.961
carA
Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
  
 
 0.957
ECL_00814
Hypothetical protein; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.948
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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