Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECL_04720Acyl transferase domain-containing protein. (304 aa)    
Predicted Functional Partners:
ECL_04724
Malonate decarboxylase beta subunit.
 
 
 0.972
ECL_04721
phosphoribosyl-dephospho-CoA transferase.
 
  
 0.971
ECL_04723
Malonate decarboxylase gamma subunit.
 
 
 0.967
fabH
3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.962
ECL_03672
3-oxoacyl-(acyl carrier protein) synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.948
acpP
Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
 
 0.947
ECL_01757
Enoyl-(acyl carrier protein) reductase.
 
 
 0.946
mdcC
Malonate decarboxylase delta subunit; Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.
 
  
 0.937
ECL_02541
3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.920
ECL_00383
3-oxoacyl-[acyl-carrier-protein] synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.912
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
Server load: low (24%) [HD]