Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pcoBCopper resistant protein PcoB. (296 aa)    
Predicted Functional Partners:
pcoA
Copper resistant protein PcoA.
 
  
 0.995
ECL_00928
Multicopper oxidase.
 
  
 0.928
pcoC
Copper resistant protein PcoC.
 
   
 0.926
pcoD
Copper resistant protein PcoD.
 
   
 0.914
ftsP
Repressor protein for FtsI; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress; Belongs to the FtsP family.
  
  
 0.870
pcoS
Two-component system, OmpR family, heavy metal sensor histidine kinase CusS; Member of a two-component regulatory system.
 
   
 0.811
pcoR
Two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR.
 
   
 0.782
ECL_04884
Hypothetical protein.
 
     0.687
cusS
Two-component system, OmpR family, heavy metal sensor histidine kinase CusS; Member of a two-component regulatory system.
 
   
 0.683
cusF-2
Cu(I)/Ag(I) efflux system periplasmic protein CusF.
 
   
 0.628
Your Current Organism:
Enterobacter cloacae
NCBI taxonomy Id: 716541
Other names: E. cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae ATCC 13047, Enterobacter cloacae subsp. cloacae str. ATCC 13047, Enterobacter cloacae subsp. cloacae strain ATCC 13047
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