gmk protein (Waddlia chondrophila) - STRING interaction network

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gmk

Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (202 aa)

Predicted Functional Partners:

guaA

0.961

pyk

0.945

nrdA

0.925

ndk1

0.917

ndk2

0.917

surE

0.913

guaC

0.912

nrdB

0.905

wcw_0705

0.900

metG

0.856

Your Current Organism:

Waddlia chondrophila

NCBI taxonomy Id: 716544
Other names: W. chondrophila WSU 86-1044, Waddlia chondrophila WSU 86-1044

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
gmk	guaA	wcw_0706	wcw_1658	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit.	0.961
gmk	guaC	wcw_0706	wcw_0845	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.912
gmk	metG	wcw_0706	wcw_0709	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.856
gmk	ndk1	wcw_0706	wcw_1543	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.917
gmk	ndk2	wcw_0706	wcw_1545	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.917
gmk	nrdA	wcw_0706	wcw_1591	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.925
gmk	nrdB	wcw_0706	wcw_1592	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribonucleoside-diphosphate reductase beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.	0.905
gmk	pyk	wcw_0706	wcw_1283	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.945
gmk	surE	wcw_0706	wcw_0879	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.913
gmk	wcw_0705	wcw_0706	wcw_0705	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Conserved hypothetical protein.	0.900
guaA	gmk	wcw_1658	wcw_0706	Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.961
guaA	guaC	wcw_1658	wcw_0845	Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit.	Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.999
guaA	metG	wcw_1658	wcw_0709	Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit.	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.801
guaA	ndk1	wcw_1658	wcw_1543	Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.431
guaA	ndk2	wcw_1658	wcw_1545	Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.431
guaA	nrdA	wcw_1658	wcw_1591	Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit.	Ribonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.663
guaA	pyk	wcw_1658	wcw_1283	Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.573
guaA	surE	wcw_1658	wcw_0879	Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit.	5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.944
guaC	gmk	wcw_0845	wcw_0706	Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.912
guaC	guaA	wcw_0845	wcw_1658	Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit.	0.999