node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gmk | guaA | wcw_0706 | wcw_1658 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit. | 0.961 |
gmk | guaC | wcw_0706 | wcw_0845 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.912 |
gmk | pheT | wcw_0706 | wcw_1542 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.536 |
gmk | ribA | wcw_0706 | wcw_1085 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.567 |
gmk | surE | wcw_0706 | wcw_0879 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.913 |
gmk | wcw_1654 | wcw_0706 | wcw_1654 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | IMP dehydrogenase/GMP reductase; Belongs to the IMPDH/GMPR family. | 0.414 |
guaA | gmk | wcw_1658 | wcw_0706 | Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.961 |
guaA | guaC | wcw_1658 | wcw_0845 | Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit. | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.999 |
guaA | pheT | wcw_1658 | wcw_1542 | Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit. | Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.917 |
guaA | purA | wcw_1658 | wcw_0315 | Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.863 |
guaA | purB | wcw_1658 | wcw_0022 | Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.751 |
guaA | purH | wcw_1658 | wcw_1655 | Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit. | Phosphoribosylaminoimidazolecarboxamideformyltra nsferase; AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Belongs to the PurH family. | 0.883 |
guaA | ribA | wcw_1658 | wcw_1085 | Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit. | Putative 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.665 |
guaA | surE | wcw_1658 | wcw_0879 | Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit. | 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.944 |
guaA | wcw_1654 | wcw_1658 | wcw_1654 | Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit. | IMP dehydrogenase/GMP reductase; Belongs to the IMPDH/GMPR family. | 0.999 |
guaC | gmk | wcw_0845 | wcw_0706 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.912 |
guaC | guaA | wcw_0845 | wcw_1658 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Bifunctional GMP synthase/glutamine amidotransferase protein; GMP synthase, PP-ATPase domain/subunit. | 0.999 |
guaC | pheT | wcw_0845 | wcw_1542 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.664 |
guaC | purA | wcw_0845 | wcw_0315 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.958 |
guaC | purB | wcw_0845 | wcw_0022 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.593 |