STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
waaFPutative lipopolysaccharide heptosyltransferase II; ADP-heptose:LPS heptosyltransferase. (355 aa)    
Predicted Functional Partners:
gseA
Putative KDO transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
  
 0.987
waaC
Putative lipopolysaccharide heptosyltransferase I; ADP-heptose:LPS heptosyltransferase.
  
  
 
0.929
glmU3
UDP-glucose pyrophosphorylase.
       0.800
hldE
Bifunctional protein hldE; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase.
  
 0.796
hldC
ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase.
 
  
 0.791
gmhA
Phosphoheptose isomerase.
 
   
 0.703
wcw_1792
Hypothetical protein.
       0.620
gpdA
Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
    0.581
ruvC
Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
     
 0.560
ruvA
Holliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.550
Your Current Organism:
Waddlia chondrophila
NCBI taxonomy Id: 716544
Other names: W. chondrophila WSU 86-1044, Waddlia chondrophila WSU 86-1044
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