STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoDRNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (555 aa)    
Predicted Functional Partners:
dnaG
DNA primase dnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 0.940
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.923
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.922
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.917
dinG
Putative ATP-dependent helicase dinG; Rad3-related DNA helicases.
  
    0.746
nusA
Transcription elongation protein nusA; Participates in both transcription termination and antitermination.
 
 
 0.713
wcw_1654
IMP dehydrogenase/GMP reductase; Belongs to the IMPDH/GMPR family.
  
 
 0.617
fur
Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
  
 
 0.611
wcw_0529
Conserved hypothetical protein.
  
  
 0.587
wcw_1764
Conserved hypothetical protein; Zn-dependent hydrolases, including glyoxylases.
  
 
 0.574
Your Current Organism:
Waddlia chondrophila
NCBI taxonomy Id: 716544
Other names: W. chondrophila WSU 86-1044, Waddlia chondrophila WSU 86-1044
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