STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (264 aa)    
Predicted Functional Partners:
SEA29742.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
 
 0.999
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.988
SEB02088.1
Sulfur carrier protein.
  
 
  0.808
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 
 0.786
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.727
SEB02051.1
2-iminoacetate synthase.
  
  
 0.572
SEB02112.1
Sulfur carrier protein ThiS adenylyltransferase.
  
  
 0.525
SEA70031.1
Sn-glycerol 3-phosphate transport system substrate-binding protein.
     
 0.482
SEA87260.1
Sn-glycerol 3-phosphate transport system substrate-binding protein.
     
 0.482
psiE
Protein PsiE.
       0.456
Your Current Organism:
Lonsdalea quercina
NCBI taxonomy Id: 71657
Other names: ATCC 29281, Brenneria quercina, CCUG 48867, CFBP 3617, CIP 105201, DSM 4561, Erwinia quercina, L. quercina, LMG 2724, LMG:2724
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