STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
maeAMalate dehydrogenase (oxaloacetate-decarboxylating). (565 aa)    
Predicted Functional Partners:
SEA69634.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 
 0.912
SEA68394.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
 
 
 0.878
SEA11039.1
FAD/FMN-containing dehydrogenase.
  
 
 0.866
SEA11118.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
   
 
 0.863
fumC
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.841
SEA59245.1
Glutamate synthase small subunit family protein.
  
 
 0.841
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.812
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.802
SDZ97252.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.765
SEA10615.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.765
Your Current Organism:
Lonsdalea quercina
NCBI taxonomy Id: 71657
Other names: ATCC 29281, Brenneria quercina, CCUG 48867, CFBP 3617, CIP 105201, DSM 4561, Erwinia quercina, L. quercina, LMG 2724, LMG:2724
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