Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEA61198.1Dihydropyrimidine dehydrogenase (NAD+) subunit PreA. (435 aa)    
Predicted Functional Partners:
SEA61168.1
Glutamate synthase (NADPH/NADH) small chain.
 0.999
SEA61233.1
Dihydropyrimidinase.
 
 0.999
SEA76867.1
Glutamate synthase (NADPH/NADH) small chain.
 
 0.985
SEA63996.1
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
    
 0.957
SEA64516.1
Aquacobalamin reductase / NAD(P)H-flavin reductase.
  
 0.956
ppnP
Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.954
SEA61263.1
N-carbamoyl-L-amino-acid hydrolase.
 
 0.947
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
 
 0.934
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
    
 0.919
SEA36842.1
Cytosine deaminase.
  
 
 0.918
Your Current Organism:
Lonsdalea quercina
NCBI taxonomy Id: 71657
Other names: ATCC 29281, Brenneria quercina, CCUG 48867, CFBP 3617, CIP 105201, DSM 4561, Erwinia quercina, L. quercina, LMG 2724, LMG:2724
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