node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDZ83599.1 | SDZ99997.1 | SAMN02982996_00389 | SAMN02982996_00685 | Uncharacterized lipoprotein. | Hypothetical protein; Belongs to the UPF0181 family. | 0.755 |
SDZ83599.1 | wecD | SAMN02982996_00389 | SAMN02982996_03224 | Uncharacterized lipoprotein. | dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.772 |
SDZ83599.1 | wecF | SAMN02982996_00389 | SAMN02982996_03227 | Uncharacterized lipoprotein. | dTDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.774 |
SDZ83599.1 | wzxE | SAMN02982996_00389 | SAMN02982996_03226 | Uncharacterized lipoprotein. | Antigen flippase; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.756 |
SDZ83599.1 | wzyE | SAMN02982996_00389 | SAMN02982996_03228 | Uncharacterized lipoprotein. | Antigen polymerase; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.774 |
SDZ83599.1 | wzzE | SAMN02982996_00389 | SAMN02982996_03221 | Uncharacterized lipoprotein. | Lipopolysaccharide biosynthesis protein WzzE; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.685 |
SDZ99997.1 | SDZ83599.1 | SAMN02982996_00685 | SAMN02982996_00389 | Hypothetical protein; Belongs to the UPF0181 family. | Uncharacterized lipoprotein. | 0.755 |
SDZ99997.1 | wecD | SAMN02982996_00685 | SAMN02982996_03224 | Hypothetical protein; Belongs to the UPF0181 family. | dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.765 |
SDZ99997.1 | wecF | SAMN02982996_00685 | SAMN02982996_03227 | Hypothetical protein; Belongs to the UPF0181 family. | dTDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.771 |
SDZ99997.1 | wzxE | SAMN02982996_00685 | SAMN02982996_03226 | Hypothetical protein; Belongs to the UPF0181 family. | Antigen flippase; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.746 |
SDZ99997.1 | wzyE | SAMN02982996_00685 | SAMN02982996_03228 | Hypothetical protein; Belongs to the UPF0181 family. | Antigen polymerase; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.770 |
SDZ99997.1 | wzzE | SAMN02982996_00685 | SAMN02982996_03221 | Hypothetical protein; Belongs to the UPF0181 family. | Lipopolysaccharide biosynthesis protein WzzE; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.461 |
wecB | wecC | SAMN02982996_03222 | SAMN02982996_03223 | UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. | 0.999 |
wecB | wecD | SAMN02982996_03222 | SAMN02982996_03224 | UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.808 |
wecB | wecE | SAMN02982996_03222 | SAMN02982996_03225 | UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | dTDP-4-amino-4,6-dideoxygalactose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.941 |
wecB | wecF | SAMN02982996_03222 | SAMN02982996_03227 | UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | dTDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.675 |
wecB | wecG | SAMN02982996_03222 | SAMN02982996_03229 | UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | UDP-N-acetyl-D-mannosaminouronate:lipid I N-acetyl-D-mannosaminouronosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. | 0.926 |
wecB | wzxE | SAMN02982996_03222 | SAMN02982996_03226 | UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | Antigen flippase; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. | 0.866 |
wecB | wzyE | SAMN02982996_03222 | SAMN02982996_03228 | UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | Antigen polymerase; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. | 0.668 |
wecB | wzzE | SAMN02982996_03222 | SAMN02982996_03221 | UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing); Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. | Lipopolysaccharide biosynthesis protein WzzE; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. | 0.877 |