Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A182F255Uncharacterized protein. (1433 aa)    
Predicted Functional Partners:
A0A182F3Z2
Uncharacterized protein.
    
 0.834
A0A182F142
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
 0.755
A0A182F663
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
 0.755
A0A182FIE5
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.719
A0A182F1K1
TGF_BETA_2 domain-containing protein.
    
 0.715
A0A182F4Y1
Uncharacterized protein.
    
 0.670
A0A182FH02
Uncharacterized protein.
   
  0.650
A0A182F6N4
Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.622
A0A182F200
CSN8_PSD8_EIF3K domain-containing protein.
    
 0.603
A0A2C9GGZ8
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
    
 0.603
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
Server load: low (22%) [HD]