Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
A0A182F447Uncharacterized protein; Belongs to the TPP enzyme family. (567 aa)    
Predicted Functional Partners:
A0A182FM70
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.934
A0A182FFL3
TPR_REGION domain-containing protein.
 
  
 0.930
A0A182FS46
Uncharacterized protein.
  
 0.900
A0A182FAJ1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.867
A0A182FKB3
FMN hydroxy acid dehydrogenase domain-containing protein.
  
 
 0.864
A0A182FAL0
PALP domain-containing protein.
  
 0.861
A0A182FBC7
HMG box domain-containing protein.
  
 0.861
A0A182FDB3
Fe-ADH domain-containing protein.
    
 0.860
A0A182FVT2
Citrate synthase; Belongs to the citrate synthase family.
    
 0.858
A0A182FL64
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.853
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
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