STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182F5B4Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites. (389 aa)    
Predicted Functional Partners:
A0A182FQY9
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety; Belongs to the peptidase C1 family.
  
 
 0.961
A0A182FH06
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
  
 
 0.959
A0A182FKK8
Aminotran_1_2 domain-containing protein.
  
 
 0.949
A0A182F331
Protein kinase domain-containing protein.
    
 0.923
A0A2Y9D0I5
Uncharacterized protein.
    
  0.918
A0A182FMI2
Uncharacterized protein; Belongs to the complex I 75 kDa subunit family.
    
 0.912
A0A182F172
Malate dehydrogenase.
  
 
 0.900
A0A182F7V6
Uncharacterized protein.
   
 
 0.897
A0A182FQJ7
NAD-dependent malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.896
A0A182FIE3
Malic enzyme.
     
 0.888
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.