STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182F5F71-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1215 aa)    
Predicted Functional Partners:
A0A182FL82
Uncharacterized protein.
    
 0.954
A0A182F6Y9
Uncharacterized protein.
   
  0.939
A0A182FJ54
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.914
A0A182FWW8
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
 0.913
A0A182FKL3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
 
0.912
A0A182FTM2
SAC domain-containing protein.
   
 
 0.908
A0A182FRQ4
WD_REPEATS_REGION domain-containing protein.
     
 0.907
A0A182FEH9
Uncharacterized protein.
     
 0.904
A0A182FK58
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 
 0.904
A0A182FRN0
Serine/threonine-protein phosphatase.
     
 0.903
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.