Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A182FA02Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (341 aa)    
Predicted Functional Partners:
A0A182FD20
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
   
 0.910
A0A182F961
S5A_REDUCTASE domain-containing protein.
   
 0.864
A0A182F9K5
Epimerase domain-containing protein.
   
 0.817
A0A182FP09
Uncharacterized protein.
   
 
 0.794
A0A182FHK8
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.733
A0A182F7H7
Nudix hydrolase domain-containing protein.
  
  
 0.704
A0A182FU16
Uncharacterized protein.
   
 
 0.689
A0A182FLM1
Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]
   
 
 0.670
A0A182F8W1
Uncharacterized protein.
  
 
 0.602
A0A182FMZ6
Uncharacterized protein.
  
 
 0.602
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
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