Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
A0A182FAM0Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (996 aa)    
Predicted Functional Partners:
A0A182FJK4
Uncharacterized protein.
    
   0.675
A0A182FS67
CUT domain-containing protein.
    
   0.675
A0A182FHD5
ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]
   
   0.664
A0A182FMM4
Uncharacterized protein.
    
 
 0.573
A0A182FJK2
Uncharacterized protein; Belongs to the synaptobrevin family.
    
   0.541
A0A182FI63
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
   0.493
A0A182F122
HP domain-containing protein.
    
   0.473
A0A182FPK8
Uncharacterized protein.
    
   0.473
A0A182FKQ1
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
   
   0.470
A0A182F1A4
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
   0.465
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
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